HORDB

ID: hor000141
Uniprot ID: Q9GSZ1
Protein name: CHH precursor-related peptide
Gene name: CHH
Organism: Carcinus maenas (Common shore crab) (Green crab)
Family: Arthropod CHH/MIH/GIH/VIH hormone family
Source: Animal
Expression: sinus gland
Disease: NA
Comments: NA
Taxonomy: Carcinus (genus), Carcinidae (family), Portunoidea (superfamily), Heterotremata, Eubrachyura, Brachyura (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region

Sequence: PSAALAVEHGTTHPLE
Length: 16(49-64)
Propeptide: MYSKTIPAMLAIITVAYLCALPHAHARSTQGYGRMDRILAALKTSSMEPSAALAVEHGTTHPLEKKQIYDTSCKGVYDRALFNDLEHVCDDCYNLYRTSYVASA
Signal peptide: MYSKTIPAMLAIITVAYLCALPHAHA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000141_AF2.pdb

hor000141_ESM.pdb

Mass:	189753	Formula:	C71H112N20O24
Absent amino acids:	CDFIKMNQRWY	Common amino acids:	A
pI:	5.33	Basic residues:	2
Polar residues:	4	Hydrophobic residues:	6
Hydrophobicity:	-12.5	Boman Index:	-1123
Half-Life:	>20 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	?	Aliphatic Index	85.63
Instability Index:	311.25	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 19523386
Title: Characterization of the Carcinus Maenas Neuropeptidome by Mass Spectrometry and Functional Genomics